Salicyl Alcohol → HCID 58022302, compound

HRID 578798Notes

Reaction equation

HRID 578798 reaction equation
[OH:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][OH:5].C(=O)([O-])[O-].[K+].[K+].[Si:16]([O:23][CH2:24][CH2:25]Br)([C:19]([CH3:22])([CH3:21])[CH3:20])([CH3:18])[CH3:17]>CN(C)C=O>[Si:16]([O:23][CH2:24][CH2:25][O:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][OH:5])([C:19]([CH3:22])([CH3:21])[CH3:20])([CH3:18])[CH3:17]

Participants

5

Reactant 3

HCID 5146Salicyl AlcoholHCID 11430Potassium CarbonateHCID 3608067(2-Bromoethoxy)-tert-butyldimethylsilane

Product 1

HCID 58022302HCID 58022302, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

To a suspension of 2-hydroxybenzyl alcohol (0.4 g) and potassium carbonate (0.67 g) in N,N-dimethylformamide (6 mL) was added 2-(tert-butyldimethylsilyloxy)ethyl bromide (1.05 mL), and the mixture was stirred at room temperature overnight.

Sources & evidence

ORD record
ord-211d0be47772441ca70d712dfe696ebf
Source dataset
uspto-grants-2015_05
Patent number
US09040693B2

Reaction notes

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