反应详情

A solution of EtOAc saturated with HCl (200 ml) was added to 4-cyano-N-(1,1 -dimethylethoxy)carbonyl-4-(2-methylphenyl)piperidine (31 mg, 0.097 mmol). The resulting mixture was allowed to react for 1 hour at room temperature. The EtOAc was removed in vacuo affording 4-cyano-4-(2-methylphenyl)piperidine hydrochloride (4i) as a white solid.

1. customto react for 1 hour at room temperature
2. customThe EtOAc was removed in vacuo