Methanesulfinic acid → HCID 22341189, compound

HRID 584668Notes

Reaction equation

HRID 584668 reaction equation
Cl[CH2:2][C:3]1[C:4](Cl)=[N:5][C:6]2[C:11]([N:12]=1)=[CH:10][C:9]([Cl:13])=[C:8]([Cl:14])[CH:7]=2.[CH3:16][S:17]([OH:19])=[O:18].[Na]>CN(C=O)C>[Cl:13][C:9]1[CH:10]=[C:11]2[C:6](=[CH:7][C:8]=1[Cl:14])[N:5]=[C:4]([S:17]([CH3:16])(=[O:19])=[O:18])[C:3]([CH2:2][S:17]([CH3:16])(=[O:19])=[O:18])=[N:12]2

Participants

5

Reactant 3

HCID 87251Methanesulfinic acidHCID 5360545SodiumHCID 22341100HCID 22341100, compound

Product 1

HCID 22341189HCID 22341189, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

To a solution of 3-chloromethyl-2,6,7-trichloroquinoxaline (150 mg, 0.53 mmol) in DMF (3 ml) was added methanesulfinic acid, sodium salt (120 mg, 1.06 mmol). The reaction mixture was stirred at room temperature overnight. The solvent was removed and the residue was purified by column chromatography (ethyl acetate:hexane 1:2) to afford the title compounds as a white solid.

Workup

  1. customThe solvent was removed
  2. customthe residue was purified by column chromatography (ethyl acetate:hexane 1:2)

Sources & evidence

ORD record
ord-da234c5bf4424624b4d98cfa6ba8c63e
Source dataset
uspto-grants-2005_08
Patent number
US06927214B1

Reaction notes

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