反应详情

温度

50 °C

A mixture of 10.6 g (0.031 mole) of 5-tetradecyloxy-2-thiophene carboxylic acid, 4.3 g (0.034 mole) of potassium carbonate, and dimethylformamide is stirred at room temperature after which 15.6 g (0.10 mole) of ethyl iodide is added. The mixture is heated at 50° C with stirring overnight and poured into water and extracted with the ether. The ether layer is washed with water and salt water and then dried over sodium sulfate, filtered, and the ether is distilled off to give 5-tetradecyloxy-2-thiophenecarboxylic acid ethyl ester.

1. additionis added
2. extractionextracted with the ether
3. washThe ether layer is washed with water and salt water
4. dry with materialdried over sodium sulfate
5. filtrationfiltered
6. distillationthe ether is distilled off