3-Cyanopyridine → 3-Cyano-1-(2-oxo-2-phenylethyl)pyridin-1-ium bromide

HRID 596719Notes

Reaction equation

C(C1C=CN=CC=1)#N.[C:9]([C:11]1[CH:12]=[N:13][CH:14]=[CH:15][CH:16]=1)#[N:10].Cl[C:18]1[CH:27]=[CH:26][C:21]([C:22](=[O:25])[CH2:23][Br:24])=[CH:20][CH:19]=1.C(Br)C(C1C=CC=CC=1)=O>>[Br-:24].[CH2:23]([N+:13]1[CH:14]=[CH:15][CH:16]=[C:11]([C:9]#[N:10])[CH:12]=1)[C:22]([C:21]1[CH:26]=[CH:27][CH:18]=[CH:19][CH:20]=1)=[O:25]

Participants

Reactant 4

HCID 793-Cyanopyridine

HCID 6259Phenacyl bromide

HCID 75064-Cyanopyridine

HCID 68303p-Chlorophenacyl bromide

Product 1

HCID 28413863-Cyano-1-(2-oxo-2-phenylethyl)pyridin-1-ium bromide

Procedure

Employing the procedure of Example II but replacing 4-cyanopyridine with a substantially equimolecular amount of 3-cyanopyridine and replacing 4-chlorophenacyl bromide with a substantially equimolecular amount of phenacyl bromide there is obtained N-(phenacyl) 3-cyanopyridinium bromide, a white solid soluble in water.

Sources & evidence

ORD record: ord-269e734c4f5a46459d6cafd6982e0127
Source dataset: uspto-grants-1977_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: USRE029153

Reaction notes

Loading…