Methyl Acrylate → HCID 86734571, compound

HRID 597184Notes

Reaction equation

HRID 597184 reaction equation
[CH3:1][O:2][C:3](=[O:6])[CH:4]=[CH2:5].[CH3:7][Si:8]([CH3:20])([CH3:19])[N:9]1[CH:14]=[CH:13][CH:12]([Si](C)(C)C)[CH:11]=[CH:10]1>O1CCCC1>[CH3:7][Si:8]([N:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]1[CH:4]([C:3]([O:2][CH3:1])=[O:6])[CH3:5])([CH3:20])[CH3:19]

Participants

4

Reactant 2

HCID 7294Methyl AcrylateHCID 132871141,4-Bis(trimethylsilyl)-1,4-dihydropyridine

Product 1

HCID 86734571HCID 86734571, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Conditions

Temperature
50 °C

Procedure

Following the procedure of Example 1, 8.6 g (0.1 mol) of acrylic acid methyl ester are brought to reaction with 22.6 g (0.1 mol) of 1,4-bis-(trimethylsilyl)-1,4-dihydropyridine. Upon addition of 20 ml of tetrahydrofuran the mixture is stirred at 50°C for 70 hours. The distillation in high vacuum yields 21.1 g (68%) of 1,4-bis-(trimethylsilyl-2-(1-carbomethoxyethyl)-1,2-dihydropyridine.

Workup

  1. distillationThe distillation in high vacuum

Sources & evidence

ORD record
ord-5011cdfa9a6b43c6a093c1ad8f42830e
Source dataset
uspto-grants-1977_03
Patent number
US04013661

Reaction notes

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