反应详情

1-Allyloxycarbonyl-N-[2-(tert-butoxycarbonylamino)ethyl]-N-[2-(4-chlorophenyl)ethyl]-piperidin-4-amine obtained in Step 1 was subjected to the deprotection reaction as described in Procedure 2 (4 N HCl in EtOAc). The crude product that was obtained in this step was used in the synthesis of Examples 8-13 without any further purification.