反应详情

温度

25 °C

A solution of the product of Example 468A (0.426 g, 1.58 mmol) in tetrahydrofuran (20 mL) was treated with ammonium formate (0.38 g, 6.03 mmol) and a catalytic amount of 20% palladium hydroxide on carbon at 70° C. for 2 hours. The reaction mixture was cooled to about 25° C., filtered through diatomaceous earth and the filtrate concentrated under reduced pressure to provide the title compound (0.244 g, 86%).

1. filtrationfiltered through diatomaceous earth
2. concentrationthe filtrate concentrated under reduced pressure