反应详情

To a solution of the product from Example 136A, iron powder and ammonium chloride in a methanol, tetrahydrofuran, and water solution was heated to reflux. The resultant mixture was filtered, and the filtrate was concentrated. Then ethyl acetate was added, stirred, filtered and concentrated under vacuum to provide the title compound (7.16 g, 90%).

1. filtrationThe resultant mixture was filtered
2. concentrationthe filtrate was concentrated
3. additionThen ethyl acetate was added
4. filtrationfiltered
5. concentrationconcentrated under vacuum