反应详情

温度

100 °C

A mixture of 4-chloro-8-(2,6-dichlorobenzoylamino)quinoline (130 mg) and 2-methoxyethylamine (210 mg) in dimethylformamide (1.5 ml) was heated for 5 hours at 100° C. The mixture was concentrated in vacuo, and the residue was purified by preparative thin layer chromatography to give 8-(2,6-dichlorobenzoylamino)-4-dimethylaminoquinoline (94 mg).

1. concentrationThe mixture was concentrated in vacuo
2. customthe residue was purified by preparative thin layer chromatography