N,N-Dimethylethylenediamine → HCID 23349902, compound

HRID 614315Notes

Reaction equation

HRID 614315 reaction equation
CO[C:3]1[CH:8]=[CH:7][N:6]=[CH:5][N:4]=1.[CH3:9][N:10]([CH2:12][CH2:13][NH2:14])[CH3:11]>C1(C)C(C)=CC=CC=1>[CH3:9][N:10]([CH3:11])[CH2:12][CH2:13][NH:14][C:3]1[CH:8]=[CH:7][N:6]=[CH:5][N:4]=1

Participants

4

Reactant 2

HCID 66053N,N-DimethylethylenediamineHCID 3038304-methoxypyrimidine

Product 1

HCID 23349902HCID 23349902, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

A solution of 4-methoxypyrimidine (12.9 g., 0.117 mole) and unsym-dimethylethylene diamine (20.7 g., 0.23 mole) in 40 ml of xylene is heated under reflux for 64 hours. The reaction is concentrated and the oil is distilled at 15 mm of Hg. 4-(2-Dimethylaminoethylamino)pyrimidine, boiling at 164°-169° C., is collected.

Workup

  1. temperatureunder reflux for 64 hours
  2. concentrationThe reaction is concentrated
  3. distillationthe oil is distilled at 15 mm of Hg
  4. custom4-(2-Dimethylaminoethylamino)pyrimidine, boiling at 164°-169° C., is collected

Sources & evidence

ORD record
ord-1bb734a4478a4fed8bce03b403cd9c07
Source dataset
uspto-grants-1979_03
Patent number
US04144338

Reaction notes

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