Potassium Carbonate → HCID 21247727, compound

HRID 619991Notes

Reaction equation

HRID 619991 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:13][CH2:12][CH:11]([CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[CH2:10][O:9]2)=[CH:4][CH:3]=1.C([O-])([O-])=O.[K+].[K+].[CH2:25](I)[CH2:26][CH2:27][CH2:28][CH2:29][CH3:30]>CN(C=O)C>[CH2:25]([O:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]2[CH2:13][CH2:12][CH:11]([CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[CH2:10][O:9]2)=[CH:6][CH:7]=1)[CH2:26][CH2:27][CH2:28][CH2:29][CH3:30]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 125271-IodohexaneHCID 21247632HCID 21247632, compound

Product 1

HCID 21247727HCID 21247727, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A mixture of 24.8 g of 2-p-hydroxyphenyl-5-pentyltetrahydropyran (obtainable by diazotization of 2-p-aminophenyl-5-pentyltetrahydropyran and hydrolysis), 6.9 g of K2CO3, 25 g of hexyl iodide and 250 ml of DMF is heated, with stirring, at 80° for 16 hours, then cooled and worked up as usual. 2-p-Hexoxyphenyl-5-pentyltetrahydropyran is obtained.

Workup

  1. temperatureis heated
  2. temperaturecooled

Sources & evidence

ORD record
ord-fc6b8145074d4db989187d3ada88a079
Source dataset
uspto-grants-1989_04
Patent number
US04818431

Reaction notes

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