Sodium Sulfite → Sodium 4-(methylsulfonyl)benzenesulfinate

HRID 628773Notes

Reaction equation

HRID 628773 reaction equation
C([O-])(O)=O.[Na+:5].[O-]S([O-])=O.[Na+].[Na+].[CH3:12][S:13]([C:16]1[CH:21]=[CH:20][C:19]([S:22](Cl)(=[O:24])=[O:23])=[CH:18][CH:17]=1)(=[O:15])=[O:14]>O>[CH3:12][S:13]([C:16]1[CH:17]=[CH:18][C:19]([S:22]([O-:24])=[O:23])=[CH:20][CH:21]=1)(=[O:15])=[O:14].[Na+:5]

Participants

5

Reactant 3

HCID 24437Sodium SulfiteHCID 516892Sodium BicarbonateHCID 27351824-Methanesulfonylbenzene-1-sulfonyl chloride

Product 1

HCID 23674706Sodium 4-(methylsulfonyl)benzenesulfinate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
80 °C

Procedure

To a solution of 0.57 g of NaHCO3 (7.1 mmol) and 1.1 g of Na2SO3 (8.8 mmol) in water (5.0 mL) were added 1.0 g (3.9 mmol) of 4-methanesulfonyl-benzenesulfonyl chloride. The reaction was heated at 80° C. for 3 h. The solvent was removed under reduced pressure. The filtrate was concentrated under reduced pressure to give sodium 4-methanesulfonyl-benzenesulfinate.

Workup

  1. customThe solvent was removed under reduced pressure
  2. concentrationThe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-eee063b1ea7847d9bb15f851c405b8b5
Source dataset
uspto-grants-2016_04
Patent number
US09315454B2

Reaction notes

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