反应详情

To a solution of methyl 3-(1,3-thiazol-2-ylsulfanyl)benzoate (76 mg) in ethyl acetate (1.5 mL) was added m-chloroperbenzoic acid (225 mg), and the mixture was stirred overnight at room temperature. The reaction mixture was poured into saturated aqueous sodium hydrogen sulfite solution, and the mixture was extracted with ethyl acetate. The extract was washed successively with saturated aqueous sodium carbonate solution and saturated brine, and dried over anhydrous magnesium sulfate, and the solvent was evaporated under reduced pressure to give the title compound (82 mg).

1. extractionthe mixture was extracted with ethyl acetate
2. washThe extract was washed successively with saturated aqueous sodium carbonate solution and saturated brine
3. dry with materialdried over anhydrous magnesium sulfate
4. customthe solvent was evaporated under reduced pressure