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HRID6332

反应详情

EQUATION

反应方程式

HRID 6332 的结构方程式

REACTANTS

反应物

3
结构：CCCCBr
HCID8002

1-Bromobutane

C4H9Br

结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：CCCCC[C@H]1CC[C@H](COc2ccc(O)c(F)c2F)CC1
HCID178418594

未命名化合物

PRODUCTS

生成物

1
结构：CCCCC[C@H]1CC[C@H](COc2ccc(OCCCC)c(F)c2F)CC1
HCID178418677

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

0.1 mol of 2,3-difluoro-4-(trans-4-pentylcyclohexyl)methoxyphenol, 0.11 mol of butyl bromide and 0.11 mol of potassium carbonate are heated for 16 hours at 100° in 100 ml of dimethylformamide (DMF). After cooling, the inorganic salts are filtered off with suction, the filtrate is concentrated, and water is added. 1-butyloxy-2,3-difluoro-4-(trans-4-pentylcyclohexyl)methoxybenzene is obtained by extraction with dichloromethane.

WORKUP

后处理

  1. temperatureAfter cooling
  2. filtrationthe inorganic salts are filtered off with suction
  3. concentrationthe filtrate is concentrated
  4. additionwater is added