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HRID634420

反应详情

EQUATION

反应方程式

HRID 634420 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1
HCID4642098

tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydropyridine-1(2H)-carboxylate

C16H28BNO4

PRODUCTS

生成物

1
结构：CC1(C)OB(C2=CCNCC2)OC1(C)C.Cl
HCID49761084

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine--hydrogen chloride (1/1)

C11H21BClNO2

收率 90%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CCOCC
溶剂HCID3283

Diethyl Ether

C4H10O

结构：COC(C)(C)C
溶剂HCID15413

Methyl tert-butyl ether

C5H12O

PROCEDURE

实验过程

tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydropyridine-1(2H)-carboxylate (2 g, 6.47 mmol) was suspended in MTBE (8.1 mL) and 2M HCl in Et2O (24 mL). The reaction was stirred rt overnight, the white precipitate formed collected by filtration and washed with Et2O to give the title compound (1.434 g, 90%).

WORKUP

后处理

  1. customthe white precipitate formed
  2. filtrationcollected by filtration
  3. washwashed with Et2O