反应详情

To a solution of 12-bromo-1-dodecanol (1 mole) in dichloromethane containing pyridinium p-toluenesulfonate (P-TSA) is added dihydropyran (2 moles). The reaction mixture is stirred for 24 hours and then washed twice with water and dried over anhydrous MgSO4. The dichloromethane is removed under reduced pressure. If necessary the resulting product is purified by chromatography on silica gel.

1. washwashed twice with water
2. dry with materialdried over anhydrous MgSO4
3. customThe dichloromethane is removed under reduced pressure
4. customIf necessary the resulting product is purified by chromatography on silica gel