反应详情

Thiophene (5.0 gm, 0.059 moles) and succinic anhydride (7.13 gm, 0.0713 moles) were taken up in dichloroethane (50 ml). Aluminium chloride (17.43 gm, 0.131 moles) was added at room temperature and the resulting mixture heated under reflux for 1 hr with stirring. The reaction mixture was cooled to room temperature, diluted with 30 ml of 1:1 mixture of water and Conc. hydrochloric acid. After stirring for 10 min the separated solid was filtered under suction, washed with water and dilute hydrochloric acid (50 ml). The solid was dried at room temp to give 9.8 gm (89%0 of the title compound, mp 103-107° C.

1. temperaturethe resulting mixture heated
2. temperatureunder reflux for 1 hr
3. stirringAfter stirring for 10 min the separated solid
4. filtrationwas filtered under suction
5. washwashed with water and dilute hydrochloric acid (50 ml)
6. customThe solid was dried at room temp