Dimethylformamide → HCID 11596163, compound

HRID 639819Notes

Reaction equation

HRID 639819 reaction equation
I[C:2]1[CH:3]=[C:4]([N:8]2[N:12]=[N:11][C:10]([CH:13]([N:15]([CH3:28])[C:16]3[N:20]([CH3:21])[C:19]([C:22]4[CH:27]=[CH:26][N:25]=[CH:24][CH:23]=4)=[N:18][N:17]=3)[CH3:14])=[N:9]2)[CH:5]=[CH:6][CH:7]=1.[CH3:29][N:30](C=O)C>[C-]#N.[Zn+2].[C-]#N>[CH3:28][N:15]([C:16]1[N:20]([CH3:21])[C:19]([C:22]2[CH:23]=[CH:24][N:25]=[CH:26][CH:27]=2)=[N:18][N:17]=1)[CH:13]([C:10]1[N:11]=[N:12][N:8]([C:4]2[CH:3]=[C:2]([CH:7]=[CH:6][CH:5]=2)[C:29]#[N:30])[N:9]=1)[CH3:14]

Participants

4

Reactant 2

HCID 6228DimethylformamideHCID 11677501HCID 11677501, compound

Product 1

HCID 11596163HCID 11596163, compound

Reagents, catalysts & solvents 1

HCID 11186Zinc cyanide (Zn(CN)2)Catalyst

Procedure

The title compound is prepared from {1-[2-(3-Iodo-phenyl)-2H-tetrazol-5-yl]-ethyl}-methyl-(4-methyl-5-pyridin-4-yl-4H-[1,2,4]triazol-3-yl)-amine (1 mmol), zinc cyanide (1.1 mmol), palladium (0) tetrakis-triphenylphosphine (0.05 mmol) in DMF (5 mL) at 80° C. overnight.

Sources & evidence

ORD record
ord-7d7c989f0ecb43639e673ab7b0860321
Source dataset
uspto-grants-2010_04
Patent number
US07691892B2

Reaction notes

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