反应详情

温度

100 °C

To a solution of N-(4′-methoxy-5-nitrobiphenyl-3-yl)acetamide (4 g, 13.98 mmol) in ethanol (50 ml) were added calcium chloride (3.1 g, 27.96 mmol, 2 eq.) and iron powder (1.45 g, 27.96 mmol, 2 eq.) and the mixture was heated at 100° C. for 2 h and filtered. The filtrate was diluted with water and extracted as in Example 1(d). The solvent was distilled off to afford the product in 87% yield (3.1 g).

1. filtrationfiltered
2. additionThe filtrate was diluted with water
3. extractionextracted as in Example 1(d)
4. distillationThe solvent was distilled off
5. customto afford the product in 87% yield (3.1 g)