Triethylamine → 3-Dimethylsilyl-5-methyl-2-oxazolidinone
Reaction equation
[CH3:1][CH:2]1[O:6][C:5](=[O:7])[NH:4][CH2:3]1.C(N(CC)CC)C.[CH3:15][SiH:16]([CH3:18])Cl>O1CCCC1>[CH3:15][SiH:16]([CH3:18])[N:4]1[CH2:3][CH:2]([CH3:1])[O:6][C:5]1=[O:7]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
A 3-dimethylsilyl-5-methyl-2-oxazolidinone was prepared in accordance with the following procedure. A stirred mixture of 60.6 grams of 5-methyl-2-oxazolidinone and 62.4 grams of triethylamine was prepared in a tetrahydrofuran solvent. To this mixture, 67.5 ml of dimethylchlorosilane was added dropwise over a period of 90 minutes.
Sources & evidence
- ORD record
- ord-5a21bbb0de154e27b3e4262db03f0ec1
- Source dataset
- uspto-grants-1988_04
- Patent number
- US04736046
Reaction notes
Loading…