Triethylamine → HCID 69986732, compound

HRID 650307Notes

Reaction equation

HRID 650307 reaction equation
C(N(CC)CC)C.[CH2:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]3[CH:20]=[CH:19][CH:18]=[CH:17][C:15]3=2)[CH:10]=[CH:9]1.[CH3:21][O:22][C:23]1[CH:28]=[CH:27][C:26](I)=[CH:25][CH:24]=1>CC([O-])=O.CC([O-])=O.[Pd+2].C(O)C>[CH3:21][O:22][C:23]1[CH:28]=[CH:27][C:26]([C:9]2[CH2:8][C:16]3[C:11]([CH:10]=2)=[CH:12][CH:13]=[C:14]2[CH:20]=[CH:19][CH:18]=[CH:17][C:15]=32)=[CH:25][CH:24]=1

Participants

6

Reactant 3

HCID 8471TriethylamineHCID 696764-IodoanisoleHCID 117450041H-Benz[e]indene

Product 1

HCID 69986732HCID 69986732, compoundYield 54%

Reagents, catalysts & solvents 2

HCID 167845palladium(II) acetateCatalystHCID 702EthanolSolvent

Procedure

20 mnl of triethylamine, 3.32 g (20 mmole) of benzindene, 4.68 g (20 mmole) of p-methoxy-phenyl-iodide and 0.134 g (0.6 mmole) of Pd(OAc)2 were stirred under reflux for 10 h. After that the mixture was cooled to room temperature and treated with 100 ml of ethanol. The crystalline precipitate was isolated, washed with ethanol and dried under vacuum to obtain 2.9 g (54%) of the mixture of two isomers.

Workup

  1. temperatureunder reflux for 10 h
  2. customThe crystalline precipitate was isolated
  3. washwashed with ethanol
  4. customdried under vacuum

Sources & evidence

ORD record
ord-91e75c7ed70442589cc2e5ef06b8913c
Source dataset
uspto-grants-2001_08
Patent number
US06271411B1

Reaction notes

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