反应详情

20 ml of triethylamine, 2.2 g (20 mmol) of indene, 5.22 , (20 mmol) of para-acetamino-iodo-benzene and 0.134 g (0.6 mmol) of Pd(OAc)2 were stirred under reflux for 10 h. After that all triethylamine was removed under reduced pressure. The residue was treated with the mixture 50 ml of dichloromethane and 50 ml of water. Organic layer was separated, washed twice with water, filtered and dried over Na2SO4. Dichloromethane was removed and the residue was recrystallized from 20 ml of EtOH. The yield of product was 13%.

1. temperatureunder reflux for 10 h
2. customAfter that all triethylamine was removed under reduced pressure
3. additionThe residue was treated with the mixture 50 ml of dichloromethane and 50 ml of water
4. customOrganic layer was separated
5. washwashed twice with water
6. filtrationfiltered
7. dry with materialdried over Na2SO4
8. customDichloromethane was removed
9. customthe residue was recrystallized from 20 ml of EtOH