反应详情

In the same manner as described in Example 29 by using (3S)-3-hydroxymethyl-1,2,3,4-tetrahydro-β-carboline (1.21 g), triethylamine (0.84 ml), CS2 (0.36 ml), 4-(N-formylamino)benzyl chloride (1.02 g) and dimethylsulfoxide (30 ml), there is prepared the title compound (1.43 g, 58%) as pale yellow powder, [α]D20 +120.2° (c=1.0, dimethylformamide); NMR (DMSO-d6, δ): 4.54 (s, 2H, ##STR12## Mass m/e: 244 (M+ -- ##STR13##