Ethyl Acetate → HCID 21710215, compound

HRID 650926Notes

Reaction equation

HRID 650926 reaction equation
C(=O)([O-])[O-].[K+].[K+].[C:7]([O:10][CH2:11][CH3:12])(=[O:9])[CH3:8].[OH:13][C:14]1[CH:21]=[CH:20][CH:19]=[CH:18][C:15]=1[C:16]#[N:17]>C(#N)C>[C:7]([O:10][CH2:11][CH2:12][O:13][C:14]1[CH:21]=[CH:20][CH:19]=[CH:18][C:15]=1[C:16]#[N:17])(=[O:9])[CH3:8]

Participants

5

Reactant 3

HCID 8857Ethyl AcetateHCID 11430Potassium CarbonateHCID 119072-Hydroxybenzonitrile

Product 1

HCID 21710215HCID 21710215, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Potassium carbonate (30 mmol) and then ethyl acetate (11 mmol) are added to a solution of 2-hydroxybenzonitrile (10 mmol) in acetonitrile. After stirring overnight, the solution is filtered and evaporated, the residue is taken up in ethyl acetate, and the organic phase is washed, dried and then evaporated to yield the expected product.

Workup

  1. filtrationthe solution is filtered
  2. customevaporated
  3. washthe organic phase is washed
  4. customdried
  5. customevaporated

Sources & evidence

ORD record
ord-37dafa11ed444634bf7101b15c2d34fd
Source dataset
uspto-grants-2001_08
Patent number
US06277851B1

Reaction notes

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