Catechol → HCID 12901626, compound

HRID 652463Notes

Reaction equation

HRID 652463 reaction equation
CO[CH:3]([NH:7][C:8]([NH2:10])=[O:9])[C:4]([OH:6])=O.[C:11]1([C:13](=[CH:15][CH:16]=[CH:17][CH:18]=1)[OH:14])[OH:12].NC(N)=O>Cl>[OH:12][C:11]1[CH:18]=[C:17]([CH:3]2[NH:7][C:8](=[O:9])[NH:10][C:4]2=[O:6])[CH:16]=[CH:15][C:13]=1[OH:14]

Participants

5

Reactant 3

HCID 289CatecholHCID 1176UreaHCID 325890NSC295473

Product 1

HCID 12901626HCID 12901626, compoundYield 44%

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

One mole (148.12 g) of α-methoxyhydantoic acid, 1.25 moles (137.64 g) of catechol, 1 mole (60.06 g) of urea and 300 ml of concentrated HCl (36 percent volume) were placed into the 2-liter flask of Preparation 1, and are stirred at 60° C. to 65° C. for 18 hours. The heterogeneous solution is filtered and is recrystallized from ethanol to give the title compound, with a melting point of 212° C.-214° C., in a yield of 44 percent.

Workup

  1. filtrationThe heterogeneous solution is filtered
  2. customis recrystallized from ethanol

Sources & evidence

ORD record
ord-7a3f3a65c5ad4c07889bf93d381ccc2f
Source dataset
uspto-grants-1987_06
Patent number
US04672101

Reaction notes

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