Dimethylformamide dimethyl acetal → 7H-Naphtho(1,2,3-ij)(2,7)naphthyridin-7-one

HRID 653616Notes

Reaction equation

HRID 653616 reaction equation
COC(OC)[N:4]([CH3:6])[CH3:5].[CH3:9][C:10]1[CH:11]=[CH:12][N:13]=C2[C:24](=[O:25])[C:23]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[C:16](=O)[C:15]=12>CN(C)C=O>[CH:20]1[CH:21]=[CH:22][C:23]2[C:24](=[O:25])[C:5]3[C:15]4[C:10]([CH:9]=[CH:6][N:4]=3)=[CH:11][CH:12]=[N:13][C:16]=4[C:18]=2[CH:19]=1

Participants

4

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 4577324-Methylbenzo(g)quinoline-5,10-dione

Product 1

HCID 3871957H-Naphtho(1,2,3-ij)(2,7)naphthyridin-7-one

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Dimethylformamide dimethyl acetal (1.50 mL, 11.34 mmol, Aldrich) was added to a solution of cleistopholine, (1.95 g, 8.73 mmol) in dimethylformamide (5 mL). The mixture was then heated for 30 min by submerging

Workup

  1. temperatureThe mixture was then heated for 30 min

Sources & evidence

ORD record
ord-77d63ea9d6e74c1ebb14483c828a2966
Source dataset
uspto-grants-1992_07
Patent number
US05128344

Reaction notes

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