Water → HCID 178437750, compound

HRID 654649Notes

Reaction equation

HRID 654649 reaction equation
[NH:1]1[CH:5]=[N:4][CH:3]=[N:2]1.[CH:6]([N:8]1[CH2:12][CH2:11][CH2:10][C:9]1=[O:13])=[CH2:7].O>C(OCC)(=O)C>[O:13]=[C:9]1[CH2:10][CH2:11][CH2:12][N:8]1[CH:6]([C:5]1[N:4]=[CH:3][NH:2][N:1]=1)[CH3:7]

Participants

5

Reactant 3

HCID 962WaterHCID 6917N-vinyl-2-pyrrolidoneHCID 92571H-1,2,4-Triazole

Product 1

HCID 178437750HCID 178437750, compoundYield 63%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

This product is synthesised, in 63% yield, from 1,2,4-triazole and 1-vinyl-2-pyrrolidinone by a similar method described in Example 1. On account of the higher water solubility of this product, ethyl acetate (3×50 ml) is used to extract it from the aqueous phase during washing. The product distils as a pale yellow oil, 150°/0.05 mbar.

Workup

  1. extractionto extract it from the aqueous phase
  2. washduring washing
  3. customThe product distils as a pale yellow oil, 150°/0.05 mbar

Sources & evidence

ORD record
ord-984c917525c14743a9f27b5d3cd21ec5
Source dataset
uspto-grants-1992_07
Patent number
US05133890

Reaction notes

Loading…