反应详情

Into a 25 liter reactor fitted with cooling and stirring means there were poured 3 liters of ethanol, 60 g of sodium and 250 g of p-chlorophenol (1.944 mol). After stirring for 1 hour there were added 3 liters of toluene and the ethanol/toluene azeotrope was removed by distillation; 2 more liters of toluene were added and also 425 g of N-cyanoethyl α -bromo-isobutyramide, (1.944 mol).

1. customInto a 25 liter reactor fitted
2. temperaturewith cooling
3. stirringAfter stirring for 1 hour there
4. customthe ethanol/toluene azeotrope was removed by distillation
5. addition2 more liters of toluene were added