Hydrogen Bromide → 2-Amino-4-(4-fluorophenyl)-5-[2-[4-(6-fluorobenzofuran-3-yl)piperidin-1-yl]ethyl]thiazole
Reaction equation
[BrH:1].[CH3:44][OH:45].[CH:35]([N:36]([CH:37]([CH3:38])[CH3:39])[CH2:40][CH3:41])([CH3:42])[CH3:43].[ClH:18].[F:19][c:20]1[cH:21][c:22]2[c:23]([c:24]([CH:27]3[CH2:28][CH2:29][NH:30][CH2:31][CH2:32]3)[cH:25][o:26]2)[cH:33][cH:34]1.[NH2:2][c:3]1[s:4][c:5]([CH2:15][CH2:16][Br:17])[c:6](-[c:8]2[cH:9][cH:10][c:11]([F:14])[cH:12][cH:13]2)[n:7]1.[OH2:46]>>[NH2:2][c:3]1[s:4][c:5]([CH2:15][CH2:16][N:30]2[CH2:29][CH2:28][CH:27]([c:24]3[c:23]4[c:22]([cH:21][c:20]([F:19])[cH:34][cH:33]4)[o:26][cH:25]3)[CH2:32][CH2:31]2)[c:6](-[c:8]2[cH:9][cH:10][c:11]([F:14])[cH:12][cH:13]2)[n:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-2e069b3ff6f543c1b76e5b9cd332e3f4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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