Acetic Acid → 7,8-Difluorochroman-6-ol
Reaction equation
[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[CH3:18][O:19][B:20]([O:21][CH3:22])[O:23][CH3:24].[CH3:1][CH2:2][CH2:3][CH2:4][Li:5].[CH3:34][C:35](=[O:36])[OH:37].[ClH:27].[F:6][c:7]1[cH:8][cH:9][c:10]2[c:15]([c:16]1[F:17])[O:14][CH2:13][CH2:12][CH2:11]2.[OH2:33].[OH:25][OH:26]>>[F:6][c:7]1[c:8]([OH:19])[cH:9][c:10]2[c:15]([c:16]1[F:17])[O:14][CH2:13][CH2:12][CH2:11]2Participants
9
Sources & evidence
- ORD record
- ord-d8de413491184760b37f94d4a0e59302
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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