Acetate → 3-(2-Methyl-4-nitro-phenyl)-acrylic Acid Methyl Ester

HRID 667061Notes

Reaction equation

HRID 667061 reaction equation
[Br:1][c:2]1[c:3]([CH3:11])[cH:4][c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1.[C:21]([CH:22]=[CH2:23])(=[O:24])[O:25][CH3:26].[C:49](#[N:50])[CH2:51][CH3:52].[CH:12]([N:13]([CH2:14][CH3:15])[CH:16]([CH3:17])[CH3:18])([CH3:19])[CH3:20].[O-:54][C:55]([CH3:56])=[O:57].[O-:58][C:59]([CH3:60])=[O:61].[Pd+2:53].[c:27]1([CH3:28])[cH:29][cH:30][cH:31][cH:32][c:33]1[P:34]([c:35]1[cH:36][cH:37][cH:38][cH:39][c:40]1[CH3:41])[c:42]1[cH:43][cH:44][cH:45][cH:46][c:47]1[CH3:48]>>[c:2]1([CH:23]=[CH:22][C:21](=[O:24])[O:25][CH3:26])[c:3]([CH3:11])[cH:4][c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 7294Methyl AcrylateHCID 7854PropionitrileHCID 80271Tri-o-tolylphosphineHCID 81531DiisopropylethylamineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 2516721-Bromo-2-methyl-4-nitrobenzene

Product 1

HCID 688396503-(2-Methyl-4-nitro-phenyl)-acrylic Acid Methyl Ester

Sources & evidence

ORD record
ord-599da9f942a64c0eb2ca14059e894452
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…