Chloride → 6-fluoro-3,4-dihydro-2-phenyl-1(2H)-naphthalenone

HRID 667250Notes

Reaction equation

HRID 667250 reaction equation
[CH3:26][N:27]([CH3:28])[CH:29]=[O:30].[Cl-:24].[F:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[C:8](=[O:12])[C:7]([C:13]([O:14][CH3:15])=[O:16])([c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)[CH2:6][CH2:5]2.[Li+:23].[OH2:25]>>[F:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[C:8](=[O:12])[CH:7]([c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)[CH2:6][CH2:5]2

Participants

6

Reactant 5

HCID 312ChlorideHCID 962WaterHCID 6228DimethylformamideHCID 28486Lithium ionHCID 57050899Methyl 6-fluoro-1,2,3,4-tetrahydro-1-oxo-2-phenyl-2-naphthalenecarboxylate

Product 1

HCID 139534336-fluoro-3,4-dihydro-2-phenyl-1(2H)-naphthalenone

Sources & evidence

ORD record
ord-b69de7a07bb64239870cec2eee8c1e43
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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