1,2-Dichloroethane → 3-(6-amino-pyridin-3-yl)-N-(3-cyano-1H-indol-2-ylmethyl)-N-methyl-acrylamide
Reaction equation
[CH2:1]([Cl:2])[CH2:3][Cl:4].[CH3:17][NH:18][CH2:19][c:20]1[nH:21][c:22]2[cH:23][cH:24][cH:25][cH:26][c:27]2[c:28]1[C:29]#[N:30].[CH:42]([N:43]([CH2:44][CH3:45])[CH:46]([CH3:47])[CH3:48])([CH3:49])[CH3:50].[NH2:5][c:6]1[cH:7][cH:8][c:9]([CH:12]=[CH:13][C:14](=[O:15])[OH:16])[cH:10][n:11]1.[O:51]=[CH:52][N:53]([CH3:54])[CH3:55].[OH2:41].[OH2:56].[OH:31][n:32]1[c:33]2[c:34]([cH:35][cH:36][cH:37][cH:38]2)[n:39][n:40]1>>[NH2:5][c:6]1[cH:7][cH:8][c:9]([CH:12]=[CH:13][C:14](=[O:16])[N:18]([CH3:17])[CH2:19][c:20]2[nH:21][c:22]3[cH:23][cH:24][cH:25][cH:26][c:27]3[c:28]2[C:29]#[N:30])[cH:10][n:11]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-da31764dff5946d79aceb4be42a1ef19
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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