Hydrochloric Acid → (1H-Indol-5-yl)-[6-(4-methylaminomethyl-phenyl)-thieno[3,2-d]pyrimidin-4-yl]-amine

HRID 668581Notes

Reaction equation

HRID 668581 reaction equation
[CH3:1][NH2:2].[CH3:30][S:31]([OH:32])(=[O:33])=[O:34].[ClH:35].[nH:3]1[cH:4][cH:5][c:6]2[cH:7][c:8]([NH:12][c:13]3[c:14]4[c:15]([n:16][cH:17][n:18]3)[cH:19][c:20](-[c:22]3[cH:23][cH:24][c:25]([CH:26]=[O:27])[cH:28][cH:29]3)[s:21]4)[cH:9][cH:10][c:11]12>>[CH3:1][NH:2][CH2:26][c:25]1[cH:24][cH:23][c:22](-[c:20]2[cH:19][c:15]3[c:14]([c:13]([NH:12][c:8]4[cH:7][c:6]5[cH:5][cH:4][nH:3][c:11]5[cH:10][cH:9]4)[n:18][cH:17][n:16]3)[s:21]2)[cH:29][cH:28]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6329MethylamineHCID 6395Methanesulfonic AcidHCID 183827594-(4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde

Product 1

HCID 18382985(1H-Indol-5-yl)-[6-(4-methylaminomethyl-phenyl)-thieno[3,2-d]pyrimidin-4-yl]-amine

Sources & evidence

ORD record
ord-c9d318ebb48147ae8eb6e6b2f31a00c2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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