Tetrahydrofuran → 6-(Hydroxymethyl)-2H-benzo[b][1,4]thiazin-3(4H)-one

HRID 668727Notes

Reaction equation

HRID 668727 reaction equation
[CH2:15]([O:16][C:17]([Cl:18])=[O:19])[CH:20]([CH3:21])[CH3:22].[CH3:28][CH2:29][N:30]([CH2:31][CH3:32])[CH2:33][CH3:34].[O:1]=[C:2]1[CH2:3][S:4][c:5]2[c:6]([cH:8][c:9]([C:12](=[O:13])[OH:14])[cH:10][cH:11]2)[NH:7]1.[O:23]1[CH2:24][CH2:25][CH2:26][CH2:27]1>>[O:1]=[C:2]1[CH2:3][S:4][c:5]2[c:6]([cH:8][c:9]([CH2:12][OH:13])[cH:10][cH:11]2)[NH:7]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 62365Isobutyl chloroformateHCID 7609933-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylic acid

Product 1

HCID 218737006-(Hydroxymethyl)-2H-benzo[b][1,4]thiazin-3(4H)-one

Sources & evidence

ORD record
ord-d00bd20eed154340aa1b69217589bdbe
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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