Acetonitrile → 3-Amino-2-cyano-6-[(4-chlorophenyl)ethynyl]pyridine
Reaction equation
[CH3:20][CH2:21][N:22]([CH2:23][CH3:24])[CH2:25][CH3:26].[CH3:27][C:28]#[N:29].[Cl:12][c:13]1[cH:14][cH:15][c:16]([I:19])[cH:17][cH:18]1.[Cu:30]([I:31])[I:32].[NH2:1][c:2]1[c:3]([C:10]#[N:11])[n:4][c:5]([C:8]#[CH:9])[cH:6][cH:7]1>>[NH2:1][c:2]1[c:3]([C:10]#[N:11])[n:4][c:5]([C:8]#[C:9][c:16]2[cH:15][cH:14][c:13]([Cl:12])[cH:18][cH:17]2)[cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-113e0dc9ca8242eda8deb2d0fc3441d3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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