Hydrochloric Acid → 4-(5-(3-(5H-pyrrolo[3,2-d]pyrimidin-4-yl)pyridin-2-ylamino)-6-methylisoquinolin-1-ylamino)benzonitrile
Reaction equation
[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[CH3:38][Si:39]([N-:40][Si:41]([CH3:42])([CH3:43])[CH3:44])([CH3:45])[CH3:46].[ClH:48].[F:22][c:23]1[n:24][cH:25][cH:26][cH:27][c:28]1-[c:29]1[c:30]2[c:31]([n:32][cH:33][n:34]1)[cH:35][cH:36][nH:37]2.[Li+:47].[NH2:1][c:2]1[c:3]2[cH:4][cH:5][n:6][c:7]([NH:13][c:14]3[cH:15][cH:16][c:17]([C:18]#[N:19])[cH:20][cH:21]3)[c:8]2[cH:9][cH:10][c:11]1[CH3:12].[Na+:53].[O-:49][C:50]([OH:51])=[O:52]>>[NH:1]([c:2]1[c:3]2[cH:4][cH:5][n:6][c:7]([NH:13][c:14]3[cH:15][cH:16][c:17]([C:18]#[N:19])[cH:20][cH:21]3)[c:8]2[cH:9][cH:10][c:11]1[CH3:12])[c:23]1[n:24][cH:25][cH:26][cH:27][c:28]1-[c:29]1[c:30]2[c:31]([n:32][cH:33][n:34]1)[cH:35][cH:36][nH:37]2Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-e32acf0167f94f8eb7cc05bb231a49fc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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