Hydrochloric Acid → N-{[2-Chloro-3-(trifluoromethyl)phenyl]methyl}-3-methyl-2-oxo-1-(3-pyridinyl)-4-imidazolidinecarboxamide

HRID 671853Notes

Reaction equation

HRID 671853 reaction equation
[CH2:29]([N:30]=[C:31]=[N:32][CH2:33][CH2:34][CH2:35][N:36]([CH3:37])[CH3:38])[CH3:39].[CH2:40]([N:41]1[CH2:42][CH2:43][O:44][CH2:45][CH2:46]1)[CH3:47].[CH3:1][N:2]1[C:3](=[O:16])[N:4]([c:10]2[cH:11][n:12][cH:13][cH:14][cH:15]2)[CH2:5][CH:6]1[C:7](=[O:8])[OH:9].[CH3:64][OH:65].[Cl:48][c:49]1[c:50]([CH2:59][NH2:60])[cH:51][cH:52][cH:53][c:54]1[C:55]([F:56])([F:57])[F:58].[Cl:61][CH2:62][Cl:63].[ClH:28].[OH2:17].[OH:18][n:19]1[c:20]2[cH:21][cH:22][cH:23][cH:24][c:25]2[n:26][n:27]1>>[CH3:1][N:2]1[C:3](=[O:16])[N:4]([c:10]2[cH:11][n:12][cH:13][cH:14][cH:15]2)[CH2:5][CH:6]1[C:7](=[O:9])[NH:60][CH2:59][c:50]1[c:49]([Cl:48])[c:54]([C:55]([F:56])([F:57])[F:58])[cH:53][cH:52][cH:51]1

Participants

10

Reactant 9

HCID 313Hydrochloric AcidHCID 887MethanolHCID 962WaterHCID 6344DichloromethaneHCID 7525EthylmorpholineHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 757711-HydroxybenzotriazoleHCID 52242072-Chloro-3-(trifluoromethyl)benzylamineHCID 671036703-Methyl-2-oxo-1-(3-pyridinyl)-4-imidazolidinecarboxylic acid

Product 1

HCID 25097733N-{[2-Chloro-3-(trifluoromethyl)phenyl]methyl}-3-methyl-2-oxo-1-(3-pyridinyl)-4-imidazolidinecarboxamide

Sources & evidence

ORD record
ord-6f233392776c4b009f268c5a90afc9c6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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