Chloride → 4-[(3-Bromophenyl)amino]-7-[3-(1-methylpiperidin-4-yl)propyloxy]-6-[(vinylcarbonyl)amino]quinazoline
Reaction equation
[C:39]([CH:40]=[CH2:41])(=[O:42])[OH:43].[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[Cl-:38].[Cl:44][CH2:45][Cl:46].[NH2:1][c:2]1[cH:3][c:4]2[c:5]([NH:23][c:24]3[cH:25][c:26]([Br:30])[cH:27][cH:28][cH:29]3)[n:6][cH:7][n:8][c:9]2[cH:10][c:11]1[O:12][CH2:13][CH2:14][CH2:15][CH:16]1[CH2:17][CH2:18][N:19]([CH3:22])[CH2:20][CH2:21]1.[O:47]1[CH2:48][CH2:49][CH2:50][CH2:51]1>>[NH:1]([c:2]1[cH:3][c:4]2[c:5]([NH:23][c:24]3[cH:25][c:26]([Br:30])[cH:27][cH:28][cH:29]3)[n:6][cH:7][n:8][c:9]2[cH:10][c:11]1[O:12][CH2:13][CH2:14][CH2:15][CH:16]1[CH2:17][CH2:18][N:19]([CH3:22])[CH2:20][CH2:21]1)[C:39]([CH:40]=[CH2:41])=[O:42]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-fda9ad611ba441cba2dd5b51c672a0c5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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