Water → N-(5-{[2-(acetylamino)[1,3]thiazolo[5,4-b]pyridin-5-yl]oxy}-2-fluorophenyl)-2-chloro-3-(1-cyano-1-methylethoxy)benzamide
Reaction equation
[CH3:17][N:18]([CH3:19])[CH:20]=[O:21].[CH3:51][N:52]([CH3:53])[C:54](=[O:55])[CH3:56].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][cH:9][c:10]1[O:11][C:12]([CH3:13])([CH3:14])[C:15]#[N:16].[Cl:45][C:46]([C:47]([Cl:48])=[O:49])=[O:50].[NH2:22][c:23]1[cH:24][c:25]([O:26][c:27]2[cH:28][cH:29][c:30]3[c:31]([n:32]2)[s:33][c:34]([NH:36][C:37]([CH3:38])=[O:39])[n:35]3)[cH:40][cH:41][c:42]1[F:43].[OH2:44]>>[Cl:1][c:2]1[c:3]([C:4](=[O:6])[NH:22][c:23]2[cH:24][c:25]([O:26][c:27]3[cH:28][cH:29][c:30]4[c:31]([n:32]3)[s:33][c:34]([NH:36][C:37]([CH3:38])=[O:39])[n:35]4)[cH:40][cH:41][c:42]2[F:43])[cH:7][cH:8][cH:9][c:10]1[O:11][C:12]([CH3:13])([CH3:14])[C:15]#[N:16]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-15494e49f6bb4e2d86ce98387b5cd5c1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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