Hydrochloric Acid → 6-bromo-N-[4-[(2,4-dioxo-1,3-thiazolidin-5-yl)methyl]phenyl]-4-oxochromene-2-carboxamide

HRID 676404Notes

Reaction equation

HRID 676404 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([c:7](=[O:14])[cH:8][c:9]([C:11](=[O:12])[OH:13])[o:10]2)[cH:15]1.[CH2:32]([N:33]=[C:34]=[N:35][CH2:36][CH2:37][CH2:38][N:39]([CH3:40])[CH3:41])[CH3:42].[ClH:31].[NH2:16][c:17]1[cH:18][cH:19][c:20]([CH2:21][CH:22]2[C:23](=[O:28])[NH:24][C:25](=[O:27])[S:26]2)[cH:29][cH:30]1.[O:53]=[CH:54][N:55]([CH3:56])[CH3:57].[OH2:58].[OH:43][n:44]1[c:45]2[cH:46][cH:47][cH:48][cH:49][c:50]2[n:51][n:52]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([c:7](=[O:14])[cH:8][c:9]([C:11](=[O:13])[NH:16][c:17]3[cH:18][cH:19][c:20]([CH2:21][CH:22]4[C:23](=[O:28])[NH:24][C:25](=[O:27])[S:26]4)[cH:29][cH:30]3)[o:10]2)[cH:15]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 962WaterHCID 6228DimethylformamideHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 757711-HydroxybenzotriazoleHCID 6888676-bromo-4-oxo-4H-chromene-2-carboxylic acidHCID 27683775-[(4-Aminophenyl)methyl]-1,3-thiazolidine-2,4-dione

Product 1

HCID 185460666-bromo-N-[4-[(2,4-dioxo-1,3-thiazolidin-5-yl)methyl]phenyl]-4-oxochromene-2-carboxamide

Sources & evidence

ORD record
ord-e8ffd91dcb52496bb2efa0a1d0266880
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…