Propargyl alcohol → HCID 6482390, compound

HRID 676842Notes

Reaction equation

HRID 676842 reaction equation
[CH2:26]([C:27]#[CH:28])[OH:29].[CH2:30]([NH:31][CH2:32][CH3:33])[CH3:34].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][C:8](=[O:9])[c:10]2[c:11](=[O:23])[c:12]3[c:13]([n:14]([CH:16]([CH3:17])[CH3:18])[cH:15]2)[s:19][c:20]([I:22])[cH:21]3)[cH:24][cH:25]1.[Cu:35]([I:36])[I:37].[Pd:38]([Cl:39])[Cl:40].[c:41]1([P:42]([c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[cH:55][cH:56][cH:57][cH:58][cH:59]1.[c:60]1([P:61]([c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)[c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[cH:74][cH:75][cH:76][cH:77][cH:78]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][C:8](=[O:9])[c:10]2[c:11](=[O:23])[c:12]3[c:13]([n:14]([CH:16]([CH3:17])[CH3:18])[cH:15]2)[s:19][c:20]([C:28]#[C:27][CH2:26][OH:29])[cH:21]3)[cH:24][cH:25]1

Participants

7

Reactant 6

HCID 7859Propargyl alcoholHCID 8021DiethylamineHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 83717Copper iodideHCID 11755179HCID 11755179, compound

Product 1

HCID 6482390HCID 6482390, compound

Sources & evidence

ORD record
ord-18eb498657f64ec198f42246232b8dec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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