Dimethylformamide → 2-Chloro-5-(4-[1,2,3]triazol-1-yl-but-1-ynyl)-pyrimidine
Reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]([Cl:8])[n:6][cH:7]1.[CH2:18]([N:19]([CH2:20][CH3:21])[CH2:22][CH3:23])[CH3:24].[CH2:9]([CH2:10][C:11]#[CH:12])[n:13]1[n:14][n:15][cH:16][cH:17]1.[Cl:25][CH2:26][Cl:27].[Cu:33]([I:34])[I:35].[O:28]=[CH:29][N:30]([CH3:31])[CH3:32].[cH:36]1[cH:37][cH:38][c:39]([P:40]([Pd:41]([P:42]([c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)([c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)([P:61]([c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)([c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)[P:80]([c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)([c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)[c:93]2[cH:94][cH:95][cH:96][cH:97][cH:98]2)([c:99]2[cH:100][cH:101][cH:102][cH:103][cH:104]2)[c:105]2[cH:106][cH:107][cH:108][cH:109][cH:110]2)[cH:111][cH:112]1>>[c:2]1([C:12]#[C:11][CH2:10][CH2:9][n:13]2[n:14][n:15][cH:16][cH:17]2)[cH:3][n:4][c:5]([Cl:8])[n:6][cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-ba16f79605cc44119f37ceb9570bf798
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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