Ammonium → 2-(5-bromo-2-chloro-pyrimidin-4-ylamino)-N-methyl-benzenesulfonamide

HRID 677227Notes

Reaction equation

HRID 677227 reaction equation
[Br:1][c:2]1[c:3]([Cl:9])[n:4][c:5]([Cl:8])[n:6][cH:7]1.[C:22](=[O:23])([O-:24])[O-:25].[CH3:30][N:31]([CH3:32])[CH:33]=[O:34].[Cl-:28].[K+:26].[K+:27].[NH2:10][c:11]1[c:12]([S:17](=[O:18])(=[O:19])[NH:20][CH3:21])[cH:13][cH:14][cH:15][cH:16]1.[NH4+:29].[OH2:35]>>[Br:1][c:2]1[c:3]([NH:10][c:11]2[c:12]([S:17](=[O:18])(=[O:19])[NH:20][CH3:21])[cH:13][cH:14][cH:15][cH:16]2)[n:4][c:5]([Cl:8])[n:6][cH:7]1

Participants

9

Reactant 8

HCID 223AmmoniumHCID 312ChlorideHCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 2899735-Bromo-2,4-dichloropyrimidineHCID 11328402-amino-N-methylbenzene-1-sulfonamide

Product 1

HCID 587483992-(5-bromo-2-chloro-pyrimidin-4-ylamino)-N-methyl-benzenesulfonamide

Sources & evidence

ORD record
ord-56dd95b7f4ff446cac7fefd443767aca
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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