Ammonium → N-(5-cyano-2-pyridinyl)-2-[1-(2,3-dichlorophenyl)pyrazolo[5,4-d]pyrimidin-4-yl]oxy-3-(2-hydroxyethoxy)propanamide

HRID 677857Notes

Reaction equation

HRID 677857 reaction equation
[C:19]([Si:20]([c:21]1[cH:22][cH:23][cH:59][cH:60][cH:61]1)([O:24][CH2:25][CH2:26][O:27][CH2:28][CH:29]([C:30](=[O:31])[NH:32][c:33]1[n:34][cH:35][c:36]([C:39]#[N:40])[cH:37][cH:38]1)[O:41][c:42]1[c:43]2[c:44]([n:45][cH:46][n:47]1)[n:48](-[c:51]1[c:52]([Cl:58])[c:53]([Cl:57])[cH:54][cH:55][cH:56]1)[n:49][cH:50]2)[c:62]1[cH:63][cH:64][cH:65][cH:66][cH:67]1)([CH3:68])([CH3:69])[CH3:70].[CH2:73]1[O:74][CH2:75][CH2:76][CH2:77]1.[CH3:2][CH2:3][CH2:4][CH2:5][N+:6]([CH2:7][CH2:8][CH2:9][CH3:10])([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:15][CH2:16][CH2:17][CH3:18].[CH3:78][CH2:79][O:80][C:81]([CH3:82])=[O:83].[Cl-:71].[F-:1].[NH4+:72]>>[OH:24][CH2:25][CH2:26][O:27][CH2:28][CH:29]([C:30](=[O:31])[NH:32][c:33]1[n:34][cH:35][c:36]([C:39]#[N:40])[cH:37][cH:38]1)[O:41][c:42]1[c:43]2[c:44]([n:45][cH:46][n:47]1)[n:48](-[c:51]1[c:52]([Cl:58])[c:53]([Cl:57])[cH:54][cH:55][cH:56]1)[n:49][cH:50]2

Participants

8

Reactant 7

HCID 223AmmoniumHCID 312ChlorideHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 178455537HCID 178455537, compound

Product 1

HCID 76550422N-(5-cyano-2-pyridinyl)-2-[1-(2,3-dichlorophenyl)pyrazolo[5,4-d]pyrimidin-4-yl]oxy-3-(2-hydroxyethoxy)propanamide

Sources & evidence

ORD record
ord-ee901fb93f534a3696c365cc3e9ef099
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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