Dimethylformamide → 1-Naphthalenecarboxamide, 6-[(2-amino-4-pyrimidinyl)oxy]-N-[4-fluoro-3-(trifluoromethyl)phenyl]-
Reaction equation
[CH2:41]([P:42]([OH:43])([OH:44])=[O:45])[CH2:46][CH3:47].[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28].[CH3:53][N:54]([c:55]1[cH:56][cH:57][n:58][cH:59][cH:60]1)[CH3:61].[F:29][c:30]1[c:31]([C:37]([F:38])([F:39])[F:40])[cH:32][c:33]([NH2:34])[cH:35][cH:36]1.[NH2:1][c:2]1[n:3][cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][c:11]3[cH:12][cH:13][cH:14][c:15]([C:19](=[O:20])[OH:21])[c:16]3[cH:17][cH:18]2)[n:7]1.[O:48]=[CH:49][N:50]([CH3:51])[CH3:52]>>[NH2:1][c:2]1[n:3][cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][c:11]3[cH:12][cH:13][cH:14][c:15]([C:19](=[O:20])[NH:34][c:33]4[cH:32][c:31]([C:37]([F:38])([F:39])[F:40])[c:30]([F:29])[cH:36][cH:35]4)[c:16]3[cH:17][cH:18]2)[n:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-0953c529c0a34c578b1030f5d9ee5964
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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