Diethylamine → 8-fluoro-4,5-dihydro-3-(3-hydroxy-3-methyl-1-butynyl)-5-methyl-6H-imidazo[1,5-a][1,4]benzodiazepin-6-one
Reaction equation
[CH2:25]([NH:26][CH2:27][CH3:28])[CH3:29].[CH3:19][C:20]([CH3:21])([C:22]#[CH:23])[OH:24].[Cu:71][I:72].[F:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:18]1)[C:7](=[O:17])[N:8]([CH3:16])[CH2:9][c:10]1[n:11]-2[cH:12][n:13][c:14]1[I:15].[Pd:30]([Cl:31])[Cl:32].[c:33]1([P:34]([c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[cH:47][cH:48][cH:49][cH:50][cH:51]1.[c:52]1([P:53]([c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[cH:66][cH:67][cH:68][cH:69][cH:70]1>>[F:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:18]1)[C:7](=[O:17])[N:8]([CH3:16])[CH2:9][c:10]1[n:11]-2[cH:12][n:13][c:14]1[C:23]#[C:22][C:20]([CH3:19])([CH3:21])[OH:24]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-fc4c75dd1cbd42e0bb9bebe8e15d6501
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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