Dichloromethane → [4-[2-Amino-4-chloro-7-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]pyrrolo[2,3-d]pyrimidin-5-yl]-2-hydroxy-2-methylbut-3-ynyl] 3,3,3-trifluoro-2-methoxy-2-phenylpropanoate
Reaction equation
[CH2:62]1[O:63][CH2:64][CH2:65][CH2:66]1.[CH3:30][O:31][C:32]([C:33](=[O:34])[Cl:35])([C:36]([F:37])([F:38])[F:39])[c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1.[CH3:46][CH2:47][N:48]([CH2:49][CH3:50])[CH2:51][CH3:52].[CH3:53][CH2:54][O:55][C:56]([CH3:57])=[O:58].[Cl:59][CH2:60][Cl:61].[NH2:1][c:2]1[n:3][c:4]([Cl:29])[c:5]2[c:6]([n:7]1)[n:8]([CH2:18][c:19]1[n:20][cH:21][c:22]([CH3:28])[c:23]([O:26][CH3:27])[c:24]1[CH3:25])[cH:9][c:10]2[C:11]#[C:12][C:13]([CH2:14][OH:15])([OH:16])[CH3:17]>>[NH2:1][c:2]1[n:3][c:4]([Cl:29])[c:5]2[c:6]([n:7]1)[n:8]([CH2:18][c:19]1[n:20][cH:21][c:22]([CH3:28])[c:23]([O:26][CH3:27])[c:24]1[CH3:25])[cH:9][c:10]2[C:11]#[C:12][C:13]([CH2:14][O:15][C:33]([C:32]([O:31][CH3:30])([C:36]([F:37])([F:38])[F:39])[c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1)=[O:34])([OH:16])[CH3:17]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-01a583d624584da5a2c6e89187e4c0cc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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