Hydrochloric Acid → 1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-piperidine-4-carboxylic acid [3-(4-fluoro-phenoxy)-phenyl]-amide

HRID 681152Notes

Reaction equation

HRID 681152 reaction equation
[CH3:36][CH2:37][N:38]([CH2:39][CH3:40])[CH2:41][CH3:42].[CH:43]([OH:44])([CH3:45])[CH3:46].[Cl:25][c:26]1[c:27]2[c:28]([n:29][cH:30][n:31]1)[nH:32][cH:33][c:34]2[CH3:35].[ClH:1].[F:2][c:3]1[cH:4][cH:5][c:6]([O:7][c:8]2[cH:9][c:10]([NH:14][C:15](=[O:16])[CH:17]3[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]3)[cH:11][cH:12][cH:13]2)[cH:23][cH:24]1>>[F:2][c:3]1[cH:4][cH:5][c:6]([O:7][c:8]2[cH:9][c:10]([NH:14][C:15](=[O:16])[CH:17]3[CH2:18][CH2:19][N:20]([c:26]4[c:27]5[c:28]([n:29][cH:30][n:31]4)[nH:32][cH:33][c:34]5[CH3:35])[CH2:21][CH2:22]3)[cH:11][cH:12][cH:13]2)[cH:23][cH:24]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 3776IsopropanolHCID 8471TriethylamineHCID 148092824-Chloro-5-methyl-7H-pyrrolo(2,3-d)pyrimidineHCID 86607289N-[3-(4-fluorophenoxy)phenyl]piperidine-4-carboxamide

Product 1

HCID 117192531-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-piperidine-4-carboxylic acid [3-(4-fluoro-phenoxy)-phenyl]-amide

Sources & evidence

ORD record
ord-3285a3a7b7c64f11b7d48066b7344de0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…